Bluetooth Ache is caused when the Mac is set to "Allow Bluetooth devices to wake this computer", and a Bluetooth device makes a connection to the Mac while the lid is closed, so it can't actually wake up properly. Some Bluetooth devices, will connect and then disconnect, repeatedly.
We've only seen this problem with Apple's M1 Macs, but it may occur with their Intel based Macs also.
A Bluetooth device makes a connection to the Mac while the lid is closed.